Browse All Trials

  • Randomized Phase III Study of Optimal Sequencing of Hormonal Therapy and Radiation in Patients with T1-T3 Prostate Cancer
  • Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Liver Tumours
  • Phase II Study of IMRT With SIB as Adjuvant Treatment for High Risk Resected Well-differentiated Thyroid Cancer.
  • A Study to Assess the effect of IMN 1207 vs Casein on survival, weight loss and quality of life in non-small cell lung cancer patients during or following chemotherapy, RT or surgery
  • The Triumph Study
  • The Metformin Active Surveillance Trial (MAST) Study
  • Pharmacogenetic Study of Irinotecan Chemotherapy
  • RTOG 0920: A Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-advanced Resected Head and Neck Cancer
  • The Effects of Chemotherapy on Cognition
  • A Study of MK1775 in Combination With Topotecan/Cisplatin in Patients With Cervical Cancer (1775-008)
  • A Trial to Assess the Safety and Effectiveness of Lutetium-177 Octreotate Therapy in Neuroendocrine Tumours
  • Pilot Study of 18F-FAZA in Assessing Early Functional Response in Patients With Inoperable Non Small Cell Lung Cancer Undergoing Radiation Therapy or Chemo-radiotherapy
  • Conventional Versus Hypofractionated Radiation in High Risk Prostate Patients
  • Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumours or Leukemia
  • Safety Study of the Proteasome Inhibitor PR-171 in Patients With Hematological Malignancies (PX-171)
  • A Study of MetMAb Administered to Patients With Advanced Non-Small Cell Lung Cancer, in Combination With Tarceva (Erlotinib)
  • Phase 3 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma
  • Adjuvant Androgen Suppression Plus Radiation Therapy for High-Risk Localized Adenocarcinoma Prostate
  • A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer
  • Temozolomide and Oral VP-16
  • Online Psychoeducational Intervention Program
  • Prostate Hypoxia FAZA
  • Radiation Therapy With Either Capecitabine or Fluorouracil Before Surgery in Treating Patients With Resectable Rectal Cancer (NSABP-R-04)
  • Reform: A Randomised Pilot Study Comparing the Efficacy of 4-weekly versus 12-weekly intravenous Bisphosphonate Therapy in Women with low risk Bone Metastases from Breast Cancer using bone resorption markers
  • The Utility of FDG-PET for Radiation Treatment in NSCLC
  • Safety Evaluation of Dexmedetomidine for EBUS-TBNA
  • The ODYSSEY Study
  • Paclitaxel and Carboplatin With or Without Celecoxib Before Surgery in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
  • A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella-Zoster Virus (VZV) Vaccine in Adults With HM Receiving Treatment With Anti-CD20 Monoclonal Antibodies (V212-013)
  • Tranexamic Acid Versus Placebo for Blood to Reduce Perioperative Bleeding Post-liver Resection
  • Personalized Oncogenomics (POG) Program of British Columbia
  • A Dose Escalation Study of MK1775 in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumours (MK-1775-001 AM7)
  • DCIS Permanent Breast Seed Implant
  • Pilot Investigation of Ultrasound Imaging and Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Locally-Advanced Breast Cancer Response to Neoadjuvant Treatment
  • A Study of R04929097 in Combination With Gemcitabine in Patients With Advanced Solid Tumours
  • Study of ABT-888 in Combination With Bortezomib and Dexamethasone in Patients With Relapsed Refractory Myeloma
  • Study of Trametinib in Advanced Cancer Patients With Hepatic Dysfunction
  • Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile
  • High-Dose-Rate Brachytherapy
  • Sunitinib or Cediranib for Alveolar Soft Part Sarcoma
  • Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-52)
  • Prostate Screening Study Using MRI in BRCA Carriers
  • Pilot Study of Whole Gland Salvage HDR Prostate Brachytherapy for Locally Recurrent Prostate Cancer
  • RATIO: Rational Approach To Immuno-Oncology
  • Does Palliative Chemotherapy Improve Symptoms in Women with Recurrent Ovarian Cancer?
  • Prospective Identification of Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases
  • Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
  • Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
  • Robotic Compared to Fixed Gantry Radiosurgery for Brain Metastases
  • Improving Quality of Life After Prostate Brachytherapy: a Comparison of HDR and LDR Brachytherapy
  • PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery
  • SF1126 for Patients With Relapsed or Refractory Neuroblastoma
  • TEM Prostate
  • Does Performing a Confirmatory Tumour Biopsy in Patients with Metastatic Breast Cancer Alter their Management?
  • Focal Salvage HDR Brachytherapy for the Treatment of Prostate Cancer
  • Hypofractionated Accelerated Post-Operative Radiation Therapy For Prostate Cancer
  • An Imaging Study in Patients With Thyroid Cancer or Head and Neck Cancer With Pertechnetate Made in a Cyclotron (C-PERT)
  • A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma
  • A Phase I/II Study of Concurrent Pemetrexed/Cisplatin/Radiation in Stage IIIA/B Non-Small Cell Lung Cancer
  • A Phase II Study of Dexamethasone in the Prophylaxis of Radiation-Induced Pain Flare
  • A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumour
  • Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery
  • A Study of MM-121 With Paclitaxel in Platinum Resistant/ Refractory Advanced Ovarian Cancers
  • GTN Therapy on Biomarkers of Immune Escape in Men With Biochemical Recurrence of Prostate Cancer After Primary Therapy
  • Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
  • Sentinel Node Biopsy in Endometrial Cancer
  • Oncology Treatment Decisions
  • Iodine I 131 Metaiodobenzylguanidine and a Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory High-Risk Neuroblastoma
  • Outpatient Platelet Transfusions in Myelodysplastic Syndromes and Leukemia: The OPTIMAL Pilot
  • Prostate Delineation: High Quality Volume CT
  • Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors
  • A Study to See if hENT1 Testing on Tumour Tissue Can Predict Response to Treatment With Gemcitabine Chemotherapy and if a Different Chemotherapy Called FOLFOX is Better Than Gemcitabine in Metastatic Pancreas Cancer
  • Neuropsychological and Behavioural Testing in Younger Patients With Cancer
  • Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
  • Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma
  • A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes
  • Effect of an Oral Supplement on the Total Energy and Protein Intake of Head and Neck Cancer Patients in the Last 2 Weeks of Radiation Therapy
  • Cisplatin, Etoposide, and Two Different Schedules of Radiation Therapy in Treating Patients With Limited Stage Small Cell Lung Cancer
  • A Study of Intensity Modulated Radiation Therapy for Pelvic Lymph Nodes and Primary Tumour in Patients with Prostate Cancer
  • CPT-11 (Irinotecan), Oxaliplatin and Xeloda (COX) in Patients with Advanced Colorectal Cancer
  • Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Peripheral T-Cell Non-Hodgkin's Lymphoma
  • Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma
  • A Study of Genetic Based Chemotherapy Dosing for Breast Cancer Patients
  • Abdominal Massage for Relief of Small Bowel Obstruction
  • Yoga Fatigue Study
  • A Study of Trametinib and GSK2141795 Multiple Myeloma
  • A Study of Cisplatin With or Without MK-1775 in Squamous Cell Cancer of the Head and Neck
  • Rituxan INF II
  • Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
  • Parent-Delivered Massage in Paediatric Cancer
  • Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy
  • Cancer, fertility and motherhood
  • Sterotactic Body Radiation Therapy for Unresectable Hepatocellular Cancer
  • CTC Pros
  • An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumours, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)
  • A Registry Study of Permanent Breast Seed Implant
  • A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer
  • Treatment of Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
  • Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population
  • Regorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard Therapy
  • Feasibility of Evaluating Gene Alteration Analysis Using Samples Obtained by EBUS-TBNA in Patients With Lung Cancer
  • Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer
  • Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer
  • Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI
  • Phase 1 Study Evaluating the Integration of Hypofractional Renal Ablative Radiation Therapy in the Setting of Metastatic Renal Cell Carcinoma
  • Collecting and Storing Tissue From Young Patients With Cancer
  • Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer
  • Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA
  • Chemotherapy and Radiation Therapy Compared With Radiation Therapy Alone in Treating Patients With High-Risk Stage I, Stage II, or Stage III Endometrial Cancer
  • Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components
  • Cervical Video Assisted Thoracoscopic Surgery (C-VATS)
  • A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)
  • Busulfan and Fludarabine as Conditioning for Allogeneic Stem Cell Transplantation: a Pharmacokinetic Study
  • Randomized Anastrozole Exercise Trial (RAE)
  • Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
  • Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
  • Computer Training Program for Younger Patients With a Brain Tumour Who Underwent Radiation Therapy
  • A Feasibility Study of an Online Intervention for Sexual Rehabilitation in Prostate Cancer
  • A comprehensive study of QOL and fatigue in patients with AML (AML QOL Fatigue)
  • Sterotactic Body Radiation Therapy for Unresectable Liver Metastases from Colorectal Cancer
  • Irinotecan pharmacogenomics
  • Osteonecrosis in Children With Acute Lymphoblastic Leukemia
  • Short Neoadjuvant Hemithoracic IMRT for MPM
  • A Randomized Phase III Study of Standard Treatment +/- Enoxaparin in Small Cell Lung Cancer
  • Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiation Therapy (SBRT)
  • Phase II Copanlisib in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
  • Stereotactic Radiation Therapy for Metastatic Kidney Cancer Being Treated With Sunitinib
  • A Study Comparing AZD-1775 (MK-1775) and Gemcitabine With Gemcitabine Alone in Ovarian, Peritoneal or Fallopian Tube Cancers
  • Reolysin in Previously Treated Advanced/Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy
  • Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies
  • Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
  • Study of MK-8242 Alone and in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia (P07649)
  • Stereotactic Radiation Therapy (SBRT) of Lung Metastasis
  • Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate Cancer
  • Preoperative Biliary Drainage in Resectable Pancreatic or Periampullary Cancer
  • Personalized PRRT of Neuroendocrine Tumours
  • A Safety and Feasibility Study of Mitotane in Prostate Cancer
  • Simple Bone Cysts in Kids
  • Pembrolizumab and Ziv-aflibercept in Treating Patients With Advanced Solid Tumours
  • Placebo Controlled Double Blind Crossover Trial of Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma
  • Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumours
  • Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences
  • Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
  • Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate Cancer
  • A Pilot Study of Gentiana lutea (radix), Zingiber officinalis, and Curcuma longa for the Treatment of Anorexia in Cancer Patients
  • Gadofosveset Trisodium (Ablavar, Gdfos) in Distinguishing Hemangiomas and Metastases: A Prospective Trial
  • OPTIM DASATINIB
  • Phase 3 Study With Carfilzomib and Dexamethasone Versus Bortezomib and Dexamethasone for Relapsed Multiple Myeloma Patients
  • HAIP-6192
  • Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging
  • In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
  • Facilitating Physical Activity Behaviour and Health Outcomes in Breast Cancer Patients Receiving Chemotherapy
  • A Study of MK-1775 in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone for Participants With Platinum-Sensitive Ovarian Tumours With the P53 Gene Mutation (MK-1775-004)
  • Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy
  • Study of Vorinostat (MK0683), an HDAC Inhibitor, in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (0683-095)
  • A Study of XL184 (Cabozantinib) in Endometrial Cancer
  • Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
  • Comparative Study of Radiation Therapy Treatments to Treat High Risk Prostate Cancer Patients
  • Safety and Anti-Tumour Study of Oral EPI-506 for Patients With Metastatic Castration-Resistant Prostate Cancer
  • Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and Neck (BIBW2992ORL)
  • Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer
  • Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction
  • Non-invasive Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Blood-Oxygen-Level Dependent Magnetic Resonance Imaging (BOLD MRI)
  • Cabazitaxel Versus the Switch to Alternative AR Targeted Therapy Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Primary Resistant Patients to Abiraterone or Enzalutamide
  • Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer
  • Protein Recommendation to Increase Muscle
  • A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
  • Study to Evaluate the Feasibility of 13-C Pyruvate Imaging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
  • Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)
  • Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma
  • A Study of (Interleukin-12) IL-12 in Patients With Acute Myelogenous Leukemia (AML)
  • Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
  • An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumours
  • MRI Brain Mets Breast (FIESTA)
  • A Study of MK-1775 in Combination With Cisplatin and Radiation in Cervical Cancer
  • Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases
  • Femoral Bone Metastases
  • Study of Palliative Radiation Therapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases
  • Personalize My Treatment (PMT) Registry
  • A Study of the Safety and Tolerability of BMS-986183 in Patients With Liver Cancer
  • Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
  • A Pilot Study To Evaluate the Effectiveness of Pulsed Time-Domain Optical Spectroscopy for Monitoring the Responses in Neoadjuvant Treatments of Locally-Advanced Breast Cancer
  • Complete Lymph Node Dissection or Observation in Treating Patients With Localized Melanoma and Sentinel Node Metastasis Who Have Undergone Sentinel Lymphadenectomy
  • Concurrent Once-daily Versus twice-daily Radiation Therapy
  • A Study Comparing Chemotherapy Dosing Based on Either Standard Body Surface Area or Lean Body Mass in Patients With Advanced Lung Cancer
  • Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis (EU-20619)
  • Prostate cancer study of CRT + Upfront ADT vs. PHPC + Salvage ADT
  • Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases
  • Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (8669-007)
  • Partial Breast Irradiation Using Interstitial Permanent Palladium-103 Seed Implant
  • Biomarkers in Tumour Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
  • Nausea and Vomiting in Children Receiving Chemotherapeautic Monotherapy
  • Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System
  • Collecting and Banking Pediatric Brain Tumour Research Specimens
  • Observational Pilot Study of 18F-Sodium Fluoride (Na18F) Whole Body Positron Emission Tomography (PET) Scans for Imaging Bone
  • Bone biopsy study
  • International Rare Histiocytic Disorders Registry (IRHDR)
  • Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL
  • A Study of Dalotuzumab + MK-2206 and Dalotuzumab + MK-0752 Combination Therapies in Participants With Advanced Cancer (MK-0646-027)
  • Melatonin and Vitamin D in Breast Cancer
  • A Study of the Safety and Efficacy of EBV Specific T-cell Lines
  • Development and Validation of a Health-related Quality of Life Instrument
  • Focal ExAblate MR-Guided Focused Ultrasound Treatment for Management of Organ-Confined Intermediate Risk Prostate Cancer
  • Study of Kidney Tumours in Younger Patients
  • A phase I clinical study of BBI608 in adult patient with advanced solid tumours.
  • A Trial Comparing Efficacy and Safety of Voriconazole Administered With Therapeutic Drug Monitoring vs. Standard Dosing
  • Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients
  • The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial
  • Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis
  • The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients With Biochemical Failure Status Post Salvage or Radical Radiation Therapy
  • An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)
  • Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer
  • A Study of Investigational Drug CFI-402257 in Patients With Advanced Solid Tumours
  • Personalized Targeted Therapy in Refractory or Relapsed Cancer in Childhood
  • INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4)
  • A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumours
  • Prostate Cancer Subclinical Metastatic Ablative MR-guided Radiation Therapy
  • Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
  • I-Scan Vs High Definition White Light (Main Study)
  • Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma
  • 18F-Fluoroazomycin Arabinoside (18F-FAZA) in Lung Cancer
  • Lu-DOTATATE Treatment in Patients With 68Ga-DOTATATE Somatostatin Receptor Positive Neuroendocrine Tumours
  • Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer
  • Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer
  • Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy
  • Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in Cancer Patients
  • ASA in Prevention of Ovarian Cancer (STICs and STONEs)
  • A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)
  • Ontario-wide Cancer TArgeted Nucleic Acid Evaluation
  • The EPIC Study
  • Study of the Predictive Marker FLT in Patients Suffering From AML
  • MRI Guided HIFU for Palliation of Painful Skeletal Metastases in Children
  • A Study to Compare Tivozanib Hydrochloride to Sorafenib in Subjects With Refractory Advanced RCC
  • A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
  • A Phase II, Multicentre Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumours or Relapsed/Refractory Synovial Sarcoma
  • Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumour Malignancies or Lymphomas
  • The ONE-MIND Study: Evaluating the Efficacy of Online Mindfulness-Based Cancer Recovery During Chemotherapy Treatment
  • A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma
  • Trial of ZW25 (Zanidatamab) in Patients With Advanced HER2-expressing Cancers
  • Len/Dex/DLI in Relapsed Multiple Myeloma After Allogeneic Stem Cell Transplant
  • Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)
  • Study to Describe the Management and the Use of Healthcare Resources in Patients With Chronic Lymphocytic Leukemia (CLL) Initiating Venetoclax in Routine Clinical Practice
  • Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
  • Real World Data on Gi(l)Otrif® Dose Adjustment
  • Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy
  • Safety and Efficacy of MAK683 in Adult Patients With Advanced Malignancies
  • A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
  • A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy
  • Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
  • First-in-human Study of ATR Inhibitor BAY1895344 in Patients With Advanced Solid Tumours and Lymphomas
  • Risk Stratified Multidisciplinary Ambulatory Management of Malignant Bowel Obstruction in Gynecological Cancers
  • Collection of Tissue Samples for Cancer Research
  • Determining Energy Needs in Colorectal Cancer
  • A Study to Evaluate Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
  • Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumours
  • NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer
  • Prostate Cancer Patient Management With 18F-DCFPyL PET/CT
  • PSMA-PET Registry for Recurrent Prostate Cancer
  • A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
  • A Phase 2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Myelofibrosis
  • Diffusion MRI-1 Imaging Database
  • Dose Optimization Study of Idelalisib in Follicular Lymphoma
  • FAZA PET/MRI Sarcoma
  • This Study Aims to Find the Best Dose of BI 907828 in Patients With Different Types of Advanced Cancer (Solid Tumours)
  • Non-operative Management for Locally Advanced Rectal Cancer
  • A Study of Glofitamab in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Non-Hodgkin Lymphomas and Participants With DLBCL
  • Tagraxofusp (SL-401) in Patients With CMML or MF
  • A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
  • A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.
  • Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.
  • A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
  • Phase III Radium 223 mCRPC-PEACE III
  • Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer
  • Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL
  • A Trial of TTI-621 for Patients With Hematologic Malignancies and Selected Solid Tumours
  • Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
  • Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to Asbestos
  • A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
  • Tissue Collection Protocol for Gastroesophageal Cancers
  • Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study
  • Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumours
  • Study of Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children With Relapsed or Refractory Solid Tumours and Leukemias
  • Receiving Radiation Therapy in the MRgRT Research Facility
  • Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)
  • Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases
  • Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer
  • A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
  • Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
  • The MATCH Study: Mindfulness And Tai Chi for Cancer Health
  • Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS
  • Cognitive Sequelae of Adjuvant Endocrine Therapy for the Treatment of Breast Cancer in Older Women
  • Evaluation of a Food Intake Modification for Lung Cancer Patients
  • Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With M+CRPC
  • Innovative Approach to Triage Oral Precancer
  • Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
  • A Study of Regorafenib in Refractory Advanced Gastro-Oesophageal Cancer
  • Evaluation of Technological Innovation in Radiation Therapy
  • Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
  • Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumours (MK-3475-158/KEYNOTE-158)
  • HDR Focal: Feasibility Study
  • Follow up to the AVANT Study up to 8 and 10 Years (Median Follow up) in Patients With Colon Carcinoma
  • Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)
  • A Study of Rucaparib Versus Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
  • An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
  • RCT of Olanzapine for Control of CIV in Children Receiving HSCT Conditioning
  • Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
  • Safety and Efficacy of Pomalidomide, Bortezomib and Low-dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
  • In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?
  • Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT
  • Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumour Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).
  • Partial Prostate Salvage High Dose Rate Brachytherapy
  • Study of Talimogene Laherparepvec In Children With Advanced Non CNS Tumours
  • Study of Pembrolizumab (MK-3475) in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)
  • A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Women With Folate Receptor (FR) Alpha Positive Advanced Epithelial Ovarian Cancer (EOC), Primary Peritoneal or Fallopian Tube Cancer
  • mDCF + Avelumab in Resectable Esophago-gastric Adenocarcinoma (EGA)
  • A Study Comparing Nivolumab, Nivolumab in Combination With Ipilimumab and Placebo in Participants With Localized Kidney Cancer Who Underwent Surgery to Remove Part of a Kidney
  • Palbociclib in Real World Practice
  • Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
  • A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy
  • Comparative Study of Use of Alpha-Blockers to Treat Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy
  • Expanded Access Program With Nivolumab Therapy for Treatment of Advanced/Metastatic SqNSCLC or Non-SqNSCLC After One Prior Systemic Regimen
  • Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas
  • Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumours (MK-4280-001)
  • Study Looking at Biomarkers in Ovarian Cancer
  • A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
  • Genomic Markers for Measuring Breast Cancer Response to Neoadjuvant Chemotherapy
  • Genomic Investigation of Unusual Responders
  • Trial of Cisplatin Plus Radiation Followed by Carbo and Taxol Vs. Sandwich Therapy of Carbo and Taxol Followed Radiation Then Further Carbo and Taxol
  • A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumours
  • Effect of Methylphenidate on Cancer-related Cognitive Impairment
  • Phase III Randomized Comparison of LDR vs. HDR Brachytherapy for Low and Intermediate Risk Prostate Cancer
  • Tavo and Pembrolizumab in Patients With Stage III/IV Melanoma Progressing on Pembrolizumab or Nivolumab Treatment
  • A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer
  • Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer
  • Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma
  • A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers
  • Diet Restriction and Exercise-induced Adaptations in Metastatic Breast Cancer
  • Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiation Therapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
  • Study of Crizotinib for ROS1 and MET Activated Lung Cancer
  • A Study of LY3435151 in Participants With Solid Tumours
  • Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumours (MK-7902-005/E7080-G000-224/LEAP-005)
  • A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer
  • Evaluation of Gd-EOB-DTPA MRI for Detection and Characterization of Liver Nodules in Cirrhotic Patients Undergoing Liver Transplantation and Potential Impact on Transplant Eligibility
  • Liver Regeneration
  • The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer
  • Liver Transplantation for Early Intrahepatic Cholangiocarcinoma
  • The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study
  • 68Ga-DOTATATE PET for Management of Neuroendocrine Tumours
  • Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption for Treatment of Glioma
  • Multiple Myeloma Molecular Monitoring Study
  • A Study of Combination Therapy With Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Participants With Relapsed or Refractory Multiple Myeloma
  • BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas
  • Calypso Guided High Precision Stereotactic Ablative Radiosurgery for Lung TUmours Using Real-Time Tumour Tracking & Respiratory Gating
  • Modifying Your Diet to Support Muscle During Cancer Treatment
  • Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer
  • Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
  • DOvEEgene: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics
  • A Phase I/II Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma
  • Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiation Therapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases
  • Impact of 18F-FDG PET-CT Versus Conventional Staging in the Management of Patients Presenting With Clinical Stage III Breast Cancer
  • Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
  • An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer
  • A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy
  • Hyperpolarized 13C MR Imaging of Lactate in Patients With Locally Advanced Cervical Cancer (LACC) Cervical Cancer
  • A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer
  • Duration of Anti-PD-1 Therapy in Metastatic Melanoma
  • Safety and Efficacy of Iron Reduction by Phlebotomy
  • Frameless Stereotactic Radiosurgery for Brain Metastases
  • A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma
  • Assessing the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy
  • A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer
  • A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma
  • An Investigational Immunotherapy Study of BMS-986249 Alone and in Combination With Nivolumab in Solid Cancers That Are Advanced or Have Spread
  • Study of Autologous Tumour Infiltrating Lymphocytes in Patients With Solid Tumours
  • Intravesical Photodynamic Therapy (PDT) in BCG Refractory/Intolerant Non-Muscle Invasive Bladder Cancer (NMIBC) Patients
  • Pre-pectoral Versus Sub-pectoral Implant Placement in Immediate Breast Reconstruction
  • Ventilation Heterogeneity Prior to Lung Resection
  • A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer
  • Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
  • Phase 3 Study of BGJ398 (Oral Infigratinib) in First Line Cholangiocarcinoma With FGFR2 Gene Fusions/Translocations
  • Needle Localization During Prostate Brachytherapy Using Power Doppler Ultrasound
  • Biomarker Directed Adjuvant Chemotherapy for Resected Pancreas Cancer
  • Radium-223 Dichloride Long-term Follow-up Program
  • ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
  • SABR for Renal Tumours
  • Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
  • Renal Cell Carcinoma Microenvironment Discovery Project
  • Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumours
  • SBRT With Combination Ipilimumab/Nivolumab for Metastatic Kidney Cancer
  • A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
  • A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
  • Alberta Cancer Exercise Hybrid Effectiveness-Implementation Study
  • Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer
  • Efficacy and Safety Study of Stereotactic Body Radiation Therapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or II Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867)
  • Neuroblastoma Maintenance Therapy Trial
  • Cell-free DNA in Hereditary And High-Risk Malignancies
  • A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer
  • Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer
  • Attribution of Toxicities Due to Radiation Therapy and Immuno-Biological Therapies
  • UM171 Expanded Cord Blood In Patients With High-Risk Acute Leukemia/Myelodysplasia
  • APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumours
  • ARREST - A Phase I Study of SABR for Poly-metastatic Disease
  • Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
  • Study of Pembrolizumab (MK-3475) in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)(MK-3475-199/KEYNOTE-199)
  • IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting
  • GRID Therapy as Palliative Radiation for Patients With Advanced and Symptomatic Tumours
  • Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer
  • A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
  • Pre-Treatment of Highly Suspicious Pigmented Skin Lesions With Interleukin-2
  • Neuroblastoma Precision Trial
  • Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid Leukemia
  • Unilateral Neck Radiation Therapy in Head and Neck Cancer
  • PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiation Therapy for Head and Neck Cancer
  • Cognitive Intervention After a Brain Tumour
  • A Phase I Study Of Panobinostat/Lenalidomide/Bortezomib/Dex for Relapsed And Relapsed/Refractory Multiple Myeloma (PanRVD)
  • MDS Mutations
  • Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
  • Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
  • A Study of SLC-0111 and Gemcitabine for Metastatic Pancreatic Ductal Cancer in Subjects Positive for CAIX
  • Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
  • Evaluating Positron Emission Mammography Imaging of Suspicious Breast Abnormalities
  • A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumours Harboring an NRG1 Fusion
  • A Study of LOXO-292 in Participants With Advanced Solid Tumours, RET Fusion-Positive Solid Tumours, and Medullary Thyroid Cancer
  • Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
  • N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan
  • Biopsies in Oncology - Prospective Study of Impact on Patient's Quality of Life.
  • Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
  • Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations
  • Preoperative vs Postoperative IMRT for Extremity/Truncal STS
  • Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
  • Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Participants With Untreated Inoperable or Metastatic Urothelial Cancer
  • An Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)
  • Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
  • GATA6 Expression as a Predictor of Response to Peri-Operative Chemotherapy in Resectable Pancreatic Adenocarcinoma
  • An Immuno-therapy Study of Nivolumab in Combination With Experimental Medication BMS-986205 Compared to Standard of Care EXTREME Regimen in First-line Recurrent/Metastatic Squamous Cell Carcinoma of Head and Neck
  • Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP)
  • Avelumab With Valproic Acid in Virus-associated Cancer
  • A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumour or Lymphoma (MK-3475-051/KEYNOTE-051)
  • AMG 176 First in Human Trial in Subjects With Relapsed or Refractory Multiple Myeloma and Subjects With Relapsed or Refractory Acute Myeloid Leukemia
  • Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?
  • Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program
  • Stereotactic Body Radiation Therapy for Breast Cancer
  • Feasibility Study of Microbial Ecosystem Therapeutics (MET-4) to Evaluate Effects of Fecal Microbiome in Patients on ImmunOtherapy
  • Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma
  • Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients
  • Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
  • A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
  • Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
  • Durvalumab vs Placebo With Stereotactic Body Radiation Therapy in Early Stage Unresected Non-small Cell Lung Cancer Patients
  • ElectroMagnetic-guided Interstitial Catheter Navigation for Gynecological brachyTherapy
  • KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
  • Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)
  • FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II)
  • A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
  • Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Cisplatin-ineligible Participants With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)
  • Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A
  • Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge
  • A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma
  • A Study to Evaluate Safety and Anti-Tumour Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid Tumours
  • Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer
  • Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumours
  • Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma
  • Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer
  • A Safety, PK and Efficacy Study of CC-92480 Monotherapy and in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)
  • Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer
  • Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer
  • Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients
  • Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
  • Selinexor and Backbone Treatments of Multiple Myeloma Patients
  • Cone-beam CT Guided Microcoil Localization of Pulmonary Nodules During Video Assisted Thoracic Surgery(VATS)
  • A Study of Long-Term Responders on Olaparib
  • Comparison of HDR vs. LDR Brachytherapy as Monotherapy for Intermediate Risk Prostate Cancer
  • Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications
  • Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
  • Dabrafenib, Trametinib, and Navitoclax in Treating Patients With BRAF Mutant Melanoma or Solid Tumours That Are Metastatic or Cannot Be Removed by Surgery
  • Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
  • A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL
  • A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumours
  • Management of Castration-Resistant Prostate Cancer With Oligometastases
  • Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC).
  • Myeloproliferative Neoplasms (MPNs) Patient Registry
  • NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)
  • Prostate Advances in Comparative Evidence (PACE)
  • Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients
  • Safety, PD & Efficacy of MT-3724 for the Treatment of Patients With Relapsed or Refractory DLBCL
  • CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies
  • Low-Dose Weekly vs High-Dose Cisplatin
  • A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer
  • A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia
  • Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer
  • De-Escalation Radiation Therapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma
  • Use of Ultrasound Imaging and Spectroscopy as Early Indicators of Locally- Advanced Breast Cancer Response to Neoadjuvant Treatment
  • Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.
  • Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL)
  • Implementing Exercise Into Clinical Practice in Breast Cancer Care
  • Blood Brain Barrier Disruption (BBBD) Using MRgFUS in the Treatment of Her2-positive Breast Cancer Brain Metastases
  • First-In-Human Study of Monoclonal Antibody BMS-986218 by Itself and in Combination With Nivolumab in Participants With Advanced Solid Tumours
  • Molecular Characteristics of Gastroesophageal Adenocarcinoma (MOCHA): A Prospective Feasibility Study
  • A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy
  • Biomarkers for Neoadjuvant Pembrolizumab in Non-Metastatic Prostate Cancer Positive by 18FDG-PET Scanning
  • A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
  • Pulmonary Physiology and Systemic Inflammatory in EO Pulmonary Events With Brigatinib Use in NSCLC and Other Diseases
  • Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
  • Safety Study of SLC-391 in Subjects With Solid Tumours
  • Magnetic Resonance-Guided Adaptive Radiation Therapy (MRgART) Using an Integrated Magnetic Resonance Linear Accelerator (MRL)
  • Master Protocol to Assess the Safety and Antitumour Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumours
  • Use of Quantitative Ultrasound to Guide Adaptive Chemotherapy Among Women With Breast Cancer
  • Randomized Embolization Trial for NeuroEndocrine Tumour Metastases To The Liver
  • FAZA PET/MRI Pancreas
  • Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells Specific in NY-ESO-1/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab
  • A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer
  • AB-16B5 Combined With Docetaxel in Subjects With Metastatic Non-Small Cell Lung Cancer (EGIA-002)
  • Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease
  • DOTATOC PET/CT for Imaging NET Patients
  • Prehabilitation to Improve Cancer Surgery Outcomes
  • Radiosurgery With or Without Whole Brain Radiation for Multiple Metastases
  • 18F-DCFPyL PET/CT in High-grade Epithelial Ovarian Cancer (PET HOC)
  • Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections
  • An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)
  • Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
  • Gut Microbiota, Anastomotic Leak and Colorectal Cancer
  • A Study of Combination Nivolumab and Ipilimumab Retreatment in Patients With Advanced Renal Cell Carcinoma
  • Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC
  • SEroma Reduction pOst MAstectomy "SEROMA Study"
  • Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer Treatments in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) (DREAMM 5)
  • A Study of Guselkumab in Participants With Familial Adenomatous Polyposis
  • Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
  • Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications
  • Three Times Weekly Symptom Screening for Children With Cancer
  • Study of Nivolumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy in Participants With High-risk, Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Primary Breast Cancer
  • Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
  • Surveillance of Complex Renal Cysts - The SOCRATIC Study
  • A Study of Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)
  • Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumour and Activation of the MAPK/ERK Pathway.
  • Study of IbrutNCT03112174inib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (SYMPATICO)
  • Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome
  • Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumours and Lymphomas
  • Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy
  • Biofeedback Rehabilitation to Improve Speaking and Eating in Public
  • A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
  • Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumours (MK-4830-001)
  • PSMA-PET: Deep Radiomic Biomarkers of Progression and Response Prediction in Prostate Cancer
  • Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • Trial of Local Consolidation Therapy (LCT) After Osimertinib for Patients With EGFR Mutant Metastatic Non-Small Cell Lung Cancer (NSCLC)
  • High Resolution Ultrasound in Pancreatic Ductal Adenocarcinoma
  • A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer
  • CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
  • MR Guidance for Liver and Pancreas
  • Platform Trial Evaluating Safety and Efficacy of BI 754091 Anti- PD-1 Based Combination Therapies in PD-(L)1 naïve and PD- (L)1 Pretreated Patient Populations With Advanced/Metastatic Solid Tumours.
  • Stereotactic Ablative Radiation Therapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer
  • A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival
  • Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
  • Efficacy and Safety Study of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in ESA Naïve Subjects Who Require Red Blood Cell Transfusions
  • Vocal-cord vs. Complete Laryngeal Radiation Therapy for Early Glottic Cancer
  • Study of Pembrolizumab and Radiation Therapy in Liver Cancer
  • Single Arm Study Using the Symphony -- MRI Guided Focused Ultrasound System for the Treatment of Leiomyomas
  • Regional Radiation Therapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
  • Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
  • A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas
  • A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma
  • A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
  • Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients
  • Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation
  • Circulating Tumour DNA in Soft Tissue Sarcoma
  • Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
  • Identification of Patients With Age-Related Clonal Hematopoiesis (ARCH) Among Cancer Survivors
  • Palliative Thoracic ImmunoRT
  • A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Subjects With Advanced Solid and Hematologic Cancers
  • Quebec Pancreas Cancer Study
  • An Investigational Immunotherapy Study of BMS-986301 Alone or in Combination With Nivolumab, and Ipilimumab in Participants With Advanced Solid Cancers
  • Three Fraction Radiation to Induce Immuno-Oncologic Response
  • Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumours Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
  • A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
  • Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
  • 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases
  • A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment
  • REtroperitoneal SArcoma Registry: an International Prospective Initiative
  • Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children
  • Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms
  • Patients With Rectal Cancer: a "Wait-and-see" Approach
  • A Randomized Trial of Pembrolizumab & Radiation Therapy Versus Radiation Therapy in High-Risk Soft Tissue Sarcoma of the Extremity
  • CFI-402257 in Combination With Paclitaxel in Patients With Advanced/Metastatic HER2-Negative Breast Cancer
  • A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
  • Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients
  • A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
  • Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumour Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumour Response to Neoadjuvant Chemotherapy
  • Effect of Tumour Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)
  • Fecal Microbial Transplantation in Combination With Immunotherapy in Melanoma Patients (MIMic)
  • Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells
  • Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)
  • Nasal Packing Following Endoscopic Endonasal Pituitary Resection
  • A Study of Nivolumab and Ipilimumab in Untreated Patients With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery
  • FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery
  • Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumours (MK-1308-001)
  • A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumours With NTRK-fusion in Children
  • Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
  • Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)
  • Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease
  • Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2
  • Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations
  • A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of AMG 510 in Subjects With Solid Tumours With a Specific KRAS Mutation (CodeBreaK 100)
  • Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma
  • Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia
  • Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
  • The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease
  • Focal HDR Brachytherapy Boost to Stereotactic Radiation Therapy
  • Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers
  • Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinoma
  • International Registry for Men With Advanced Prostate Cancer (IRONMAN)
  • The UNSCARRed Study: UNresctable Squamous Cell Carcinoma Treated With Avelumab and Radical Radiation Therapy
  • Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumours
  • Cabozantinib to Treat Recurrent Liver Cancer Post Transplant
  • Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive
  • Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.
  • Study of Safety and Tolerability of BCA101 Alone and in Combination With Pembrolizumab in Patients With EGFR-driven Advanced Solid Tumours
  • Ex-Vivo COF Study for Lung Cancer Observation
  • A Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma
  • An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)
  • A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
  • Prostate Cancer Biomarker Enrichment and Treatment Selection
  • A Study to See Whether Stereotactic Body RadioTherapy (SBRT) Can Shrink Tumours Within the Liver Safely
  • WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism
  • Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumours
  • Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
  • Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma
  • Relationship Between 18FDG PET/MRI Patterns and ctDNA to Predict HCC Recurrence After Liver Transplantation
  • A Study to Evaluate Long-term Safety in Subjects Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
  • Maintenance With Selinexor/Placebo After Combination Chemotherapy in Participants With Endometrial Cancer [SIENDO]
  • Assessment of Left-sided Cardiac Sparing Through the Use of 3-dimensional Surface Matching-based Deep Inspiration Breath Hold and Active Breathing Control
  • A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008)
  • Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer
  • Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients
  • A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers
  • Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC
  • Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
  • Prehab for Cancer Surgery
  • Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2+ Gastric Cancer (DESTINY-Gastric03)
  • A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases
  • Cisplatin + Radiation Therapy vs Durvalumab + Radiation Therapy Followed by Durvalumab vs Durvalumab + Radiation Therapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC
  • Feasibility of Multi-Energy Digital Radiography Detector for Lung Lesions Detection
  • Brentuximab Vedotin and Nivolumab in Treating Participants With Early Stage Classic Hodgkin Lymphoma
  • Stereotactic Ablative Radiation Therapy for Comprehensive Treatment of 4-10 Oligometastatic Tumours
  • Smart Phone App for COLOnoscopic PREParation
  • A Phase 1 Study of [225Ac]-FPI-1434 Injection
  • SUPR-3D: Simple Unplanned Palliative Radiation Therapy Versus 3D Conformal Radiation Therapy for Patients With Bone Metastases
  • Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumours Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
  • Elotuzumab, Pomalidomide, & Dexamethasone (Elo-Pom-Dex) With Second Autologous Stem Cell Transplantation for Relapsed Multiple Myeloma
  • Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumours
  • Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer
  • Carotid PET/MRI With DOTATATE in Patients Post Head and Neck Radiation Therapy
  • Stereotactic Ablative Radiation Therapy for Oligo-Progressive Non Small Cell Lung Cancer
  • Tumour Immunotherapy and Microbiome Analysis
  • A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)
  • Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients
  • 89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study
  • Sirolimus for Retinal Astrocytic Hamartoma
  • A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)
  • INVINCIBLE TRIAL: Intratumoural INT230-6 in Breast Cancer
  • Stereotactic Body Radiation Therapy for Patients With Breast Cancer Oligometastasis
  • Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer
  • Study of Out of Specification for Tisagenlecleucel
  • Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Locally Advanced Pancreatic Cancer
  • To Evaluate Safety, Tolerability, and Clinical Activity of the Antibody-drug Conjugate, GSK2857916 Administered in Combination With Lenalidomide Plus Dexamethasone (Arm A), or in Combination With Bortezomib Plus Dexamethasone (Arm B) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
  • A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer
  • Viscoelasticity Imaging to Assess Liver Cancer
  • Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma (PRE-MERIDIAN)
  • A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma
  • A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
  • Pan-Canadian Lung Cancer Observational Study (PALEOS)
  • A Phase I Study of BTRC4017A in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers
  • NCI COVID-19 in Cancer Patients, NCCAPS Study
  • Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery
  • Study of RP-3500 in Advanced Solid Tumours
  • Investigation of Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
  • Study of Molecular Response Adaptive Immuno-Chemotherapy in Patients With NSCLC
  • Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer
  • Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumours
  • Stereotactic Body Radiation Therapy for Osseous Low Alpha-Beta Resistant Metastases for Pain Relief
  • The Canada Lymph Node Score Project: A Crossover Trial
  • Study to Evaluate Imetelstat (GRN163L) in Subjects With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
  • Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer
  • Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer
  • A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck
  • Immune Resistance Interrogation Study
  • A Study of ASP1948, Targeting an Immune Modulatory Receptor as a Single Agent and in Combination With a PD-l Inhibitor (Nivolumab or Pembrolizumab) in Subjects With Advanced Solid Tumours
  • Saltikva for Metastatic Pancreatic Cancer
  • FLT-PET / MRI Brain Mets
  • Study of SRF617 in Patients With Advanced Solid Tumours
  • A Study of Intratumoural/Intralesional Administration of V938 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic or Recurrent Malignancies (V938-001)
  • Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma
  • Evaluation of Deployment Capability and Accuracy of an Outside the Scope (OTS), Detachable Catheter System for Ablation of Peripheral Lung Lesions: An Ex-Vivo Human Lung Model Study
  • Single Fractions SBRT for Prostate Cancer
  • Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBC
  • Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study
  • Master Protocol to Assess the Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumours
  • A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
  • A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer
  • Determinants of Acquired Endocrine Resistance in Metastatic Breast Cancer: A Pilot Study
  • Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Renal Cell Carcinoma Patients
  • Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.
  • Ex-vivo Delivery of Rituximab to Prevent PTLD in EBV Mismatch Lung Transplant Recipients: A Pilot Trial
  • Childhood Cancer Predisposition Study (CCPS)
  • Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care
  • A Phase 1/2 Safety Study of Intratumourally Dosed INT230-6
  • A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
  • SUNSET: SBRT for Ultra-central NSCLC- a Safety and Efficacy Trial
  • A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumours
  • Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis
  • Project: Every Child for Younger Patients With Cancer
  • International Diffuse Intrinsic Pontine Glioma (DIPG) Registry and Repository
  • Bevacizumab and Anetumab Ravtansine or Paclitaxel in Treating Patients With Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • DOvEE - Diagnosing Ovarian & Endometrial Cancer Early
  • Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumours
  • Hypofractionated Whole-Pelvis Radiation Therapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer
  • A Study of TAK-676 and TAK-676 in Combination With Pembrolizumab in Adults With Advanced Solid Tumours
  • Durvalumab Treatment in Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Toxicity
  • A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
  • Study of Nivolumab Plus Ipilimumab, Ipilimumab or Cabazitaxel in Men With Metastatic Castration-Resistant Prostate Cancer
  • A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer
  • A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumours With a KRAS G12C Mutation
  • A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology
  • Tumour-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
  • Intraoperative Radiation Therapy in Newly Diagnosed Glioblastoma Multiforme
  • Study of Pembrolizumab (MK-3475) Versus Placebo After Complete Resection of High-Risk Stage III Melanoma (MK-3475-054/KEYNOTE-054)
  • A Study to Try to Bring Back Radioiodine Sensitivity in Patients With Advanced Thyroid Cancer.
  • A Safety Trial of Fedratinib in Subjects With DIPSS, Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib With Concomitant Luspatercept for Subjects With Anemia
  • Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
  • Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer
  • A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer
  • Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)
  • A Study of MK-0482 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumours (MK-0482-001)
  • Haplo vs. URD in AML
  • A Randomized, Multicentre Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant Chemotherapy
  • The Use and Effectiveness of Balloon for Endobronchial Ultrasonography
  • Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation
  • A Study of Debio 1143 (Xevinapant) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiation Therapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy
  • A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumours
  • Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumours or With Liver Metastases of Solid Tumours
  • Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies
  • Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)
  • Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor
  • A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
  • A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumours (ARTISTRY-2)
  • Hypofractionated LocoRegional Radiation Therapy in Breast Cancer
  • INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients
  • Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
  • FAZA PETMRI Gastro-Oesophageal Study
  • A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (Intrinsic)
  • A Study to Evaluate the Triplet Combination of Bempegaldesleukin (Bempeg/NKTR-214) Plus Nivolumab and Axitinib and the Doublet Combination of Nivolumab and Axitinib in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread
  • Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer
  • Tazemetostat and Pembrolizumab in Treating Patients With Locally Advanced or Metastatic Urothelial Carcinoma
  • Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving INC280 Treatment as Single Agent or in Combination With Other Treatments.
  • Chemoradiotherapy for Advanced Esophageal Cancer
  • Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
  • 3TMPO (Triple-Tracer Strategy Against Metastatic Prostate Cancer
  • Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia
  • Artificial Intelligence for Real-time Detection and Monitoring of Colorectal Polyps
  • A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)
  • GEN3013 Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
  • A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
  • A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Rituximab in Subjects With Relapsed or Refractory Non-hodgkin Lymphomas (R/R NHL)
  • Post SBRT Pulmonary Metastasectomy (PSPM) Trial
  • Prospective Analysis of Intestinal Microbiome and Autoimmune Panels as Predictors of Toxicity in ImmunOncology Patients
  • Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of ABBV-151 as a Single Agent and in Combination With ABBV-181 in Participants With Locally Advanced or Metastatic Solid Tumours
  • Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)
  • A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)
  • Toward a Comprehensive Supportive Care Intervention for Older or Frail Men With mCRPC
  • Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
  • A Feasibility Study Evaluating Surgery for Mesothelioma After Radiation Therapy Using Extensive Pleural Resection
  • Real Time MRI Fused to Cone Beam CT Guided Biopsies of the Prostate.
  • A Study of Salvage Radiation Therapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery
  • SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients
  • 5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:
  • TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence
  • A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumours With Hepatic Metastases
  • Perfexion Registration Using CBCT
  • Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)
  • Carbon-Fibre Accessory (CARA) for Supine Breast Positioning to Reduce Toxicity in Whole Breast Radiation Therapy
  • Protein Needs in Cancer
  • A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC)
  • A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
  • Liquid Biopsy Evaluation and Repository Development at Princess Margaret
  • A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
  • A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer
  • Stereotactic Pelvic Adjuvant Radiation TherApy in Cancers of the UteruS
  • Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
  • A Study of ASP1951 in Subjects With Advanced Solid Tumours
  • A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma
  • Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)
  • Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer
  • (PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis
  • Pancreatic Adenocarcinoma Neoadjuvant Combination Chemotherapy and Stereotactic Body Radiation Therapy Before Surgery
  • A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
  • ATG Plus PTCy vs ATG for CGVHD Prophylaxis
  • Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's Macroglobulinemia
  • Pre-operative RadiothErapy for Soft Tissue SarcOmas
  • AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer.
  • Stereotactic Ablative Radiation Therapy for Abiraterone-Resistant, Oligoprogressive Metastatic Prostate Cancer
  • M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)
  • 177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer
  • Multi-Centre Study of GSK2857916 in Combination With Pomalidomide and Dex
  • A Study to Desensitize Allergic Reactions to Treatments for Blood Disorders
  • LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
  • Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab
  • Study of I-131-1095 Radiation Therapy in Combination With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer Who Are Chemotherapy Naive and Have Progressed on Abiraterone
  • Evaluating Whether Integration of Prognostic and Predictive Algorithms Into Routine Clinical Practice Effect Whether Oncologists Order Multigene Assays in Patients With Early Stage Breast Cancer
  • RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy
  • Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma
  • Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain
  • Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007)
  • Surpass: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Tumours
  • Post-Prostatectomy Linac-Based Ultrahypofractionated Radiation Therapy for Patients With Localized Prostate Cancer
  • Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer
  • A Study to Evaluate the Safety and Tolerability of RO7296682 in Participants With Advanced Solid Tumours.
  • Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer
  • A Study to Determine the Recommended Dose and Regimen and Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)
  • Pre-operative Inspiratory Muscle Training Program to Prevent Pulmonary Complications After Thoracic Surgery
  • Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
  • A Study of ZW25 (Zanidatamab) With Palbociclib Plus Fulvestrant in Patients With HER2+/HR+ Advanced Breast Cancer
  • A Study of Mirvetuximab Soravtansine vs. Investigator's Choice of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression
  • A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)
  • Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
  • Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer
  • Accelerating Lung Cancer Diagnosis Through Liquid Biopsy
  • Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck
  • Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With CLL or SLL
  • Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer
  • Tailored Adjuvant Therapy in POLE-mutated and p53-wildtype Early Stage Endometrial Cancer
  • A Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Participants With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant
  • Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer
  • Testing Atezolizumab in Patients >= 2 Years Old With Newly Diagnosed, Unresectable, or Metastatic Clear Cell Sarcoma or Chondrosarcoma
  • Phase I Trial of PCLX-001 in B-cell Non-Hodgkin Lymphoma and Advanced Solid Malignancies
  • Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial
  • A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer
  • A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (LEAP-010) (MK-7902-010)
  • Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
  • Evaluation of a Novel Axillary Lymph Node Ink Localization Technique: A Feasibility Study
  • Physiotherapy Treatment for Gynecological Cancer Survivors With Urinary Incontinence
  • Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumours, Including Central Nervous System Tumours
  • A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
  • Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET
  • Molecular Profiling of Advanced Biliary Tract Cancers
  • Study of Sasanlimab (PF-06801591) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-Risk Non-Muscle Invasive Bladder Cancer
  • Study of Circulating Tumour DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN)
  • First in Human Study of M6223
  • Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
  • A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That Has Invaded the Muscle Wall of the Bladder and Who Cannot Get Cisplatin, a Type of Medicine Given to Treat Bladder Cancer.
  • Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)
  • Study of CC-96191 in Participants With Relapsed or Refractory Acute Myeloid Leukemia
  • Study of DCC-3014 in Patients With Advanced Tumours and Tenosynovial Giant Cell Tumour
  • Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumours and Ewing Sarcoma
  • CBF and NCF Changes With Brain Radiation
  • Talazoparib and Thoracic RT for ES-SCLC
  • A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma
  • Topotecan Episcleral Plaque for Treatment of Retinoblastoma
  • Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM
  • Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency
  • A Study Comparing the Efficacy and Safety of Nivolumab in Combination With Bacillus Calmette-Guerin (BCG) Versus BCG Alone in Participants With High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC)
  • A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy
  • Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumours and TRK Fusion Relapsed Acute Leukemia
  • A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma
  • Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II
  • An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer
  • Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 Mutation
  • Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.
  • Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)
  • Analysis of Patterns of Recurrence in Head and Neck Cancer Using Clinicopathomic Markers
  • 3D Printed Mask for GBM and Brain Mets
  • Effect of Tumour Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)
  • A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant, Hormone Receptor-Positive, Her2-Negative, Locally Advanced or Metastatic Breast Cancer
  • Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis
  • Phase 2 Study of Poziotinib in Patients With NSCLC Having EGFR or HER2 Exon 20 Insertion Mutation
  • Major Radiation Reduction for HPV+ Oropharyngeal Carcinoma
  • Efficacy and Safety of Pembrolizumab (MK-3475) With Lenvatinib (E7080/MK-7902) vs. Docetaxel in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease (PD) After Platinum Doublet Chemotherapy and Immunotherapy (MK-7902-008/E7080-G000-316/LEAP-008)
  • Randomized Phase III Trial With Mepitel Film for the Prophylaxis of Radiation Dermatitis in Breast Cancer Patients
  • A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
  • Dynamic Whole Body Positron Emission Tomography/Computed Tomography Imaging
  • A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation
  • Ultrasound Spectroscopy as Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers
  • Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
  • SUV on PSMA PET/CT in Non-Prostate Tumours
  • Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamide
  • Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis
  • Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015)
  • Study of AMG 650 in Adult Participants With Advanced Solid Tumours
  • Study to Evaluate the Safety and Preliminary Efficacy of 177Lu-OPS201 in NETs
  • Non-ablative Oligofractionated Radiation Therapy Before Surgical Transplantation As Radiovaccination
  • Celiac Plexus Radio-Surgery for Pain Management
  • A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis
  • Preventing Toxicity in Renal Cancer Patients Treated With Immunotherapy Using Fecal Microbiota Transplantation
  • First-in-human Study of M4076 in Advanced Solid Tumours (DDRiver Solid Tumours 410)
  • Magnetic Occult Lesion Localization Instrument (MOLLI) Guidance System for Breast Lesion Localization
  • A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumours
  • Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer Patients
  • Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)
  • Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations
  • Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC
  • Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer
  • Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia
  • CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib
  • A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma
  • Study of Chemoradiotherapy With or Without Pembrolizumab (MK-3475) For The Treatment of Locally Advanced Cervical Cancer (MK-3475-A18/KEYNOTE-A18/ENGOT-cx11/GOG-3047)
  • Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL
  • Study To Evaluate Safety, Pharmacokinetics, Pharmacodynamics, And Preliminary Anti-Tumour Activity Of RO7122290 In Combination With Cibisatamab With Obinutuzumab Pre-Treatment
  • Study of CPI-0610 in Myelofibrosis (MF)
  • FACE-Q in Facial Reconstructive Surgery: A Prospective Database
  • The PET- Retroperitoneal Sarcoma Study
  • Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma
  • Topotecan Episcleral Plaque for Treatment of Retinoblastoma
  • Nivolumab Plus Pemetrexed for Head and Neck Squamous Cell Carcinoma
  • Heal-Me Personalized Online Nutrition and Exercise Routines
  • A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer
  • Global CALM Implementation Study
  • An Open-Label, Randomized, Multicentre Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis
  • A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in the Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumours
  • This Study Will Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC.
  • A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients
  • Imvamune Vaccine for the Treatment of Non-melanoma Skin Cancer
  • Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC
  • A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumours
  • A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies
  • Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
  • Oncologist-Initiated Cancer Genetic Testing for Pancreatic Cancer Patients
  • PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer
  • The Person-centreed Evolution of Radiation Therapy Services in Ontario Study
  • A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.
  • A Safety and Preliminary Efficacy Study of CC-99282 in Combination With Obinutuzumab in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
  • Pediatric Oncology Recovery Trial After Surgery
  • Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer
  • Limited Adjuvant Endocrine Therapy for Low Risk Breast Cancer
  • A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)
  • International Validation Study of Sentinel Node Biopsy in Early Cervical Cancer (SENTICOLIII)
  • A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Atezolizumab in Patients With NRAS-mutant Advanced Melanoma.
  • Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B)
  • PRecision Oncology Evidence Development in Cancer Treatment - Clinical: PREDiCTc
  • BRAINFUL (BRAIN Tumour Focused Ultrasound-enabled Liquid Biopsy) Trial
  • Heavy Lifting Strength Training in Head and Neck Cancer Survivors
  • Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled Trial
  • Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma
  • First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b
  • Acetyl-Amantadine as a Biomarker in Patients With Glioblastoma
  • Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer
  • Multicentre Phase II Study of Transanal TME (taTME)
  • A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study
  • Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer
  • Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery
  • Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)
  • Advanced Endo-therapeutic Procedure : Registry-based Observational Study
  • BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
  • Impact of a Patient-Centreed Program for Low Anterior Resection Syndrome A Multicentre Randomized Controlled Trial
  • An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)
  • TAK-788 as First-line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations
  • Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant
  • Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitor BMS-986158 in Pediatric Cancer
  • CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)
  • A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
  • A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
  • Lung Cancer Cryo-Activation as a Novel Approach to Augment Immunotherapy Efficacy (CRYOVATE)
  • Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer
  • CFI-400945 and Durvalumab in Patients With Advanced Triple Negative Breast Cancer
  • Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma
  • A Study of Teclistamab, in Participants With Relapsed or Refractory Multiple Myeloma
  • Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)
  • Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer
  • Platform Study of Novel Ruxolitinib Combinations in Myelofibrosis Patients (ADORE)
  • 68Ga-PSMA-11 PET/CT for Assessment of High Risk or Recurrent Prostate Cancer
  • Cisplatin Induced Kidney Toxicity
  • Stellate Ganglion Block for Major Depressive Disorder.
  • A Study of miRNA 371 in Patients With Germ Cell Tumours
  • A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas
  • An Impact Assessment of a Culturally Tailored Online Psychosocial Program for Chinese Immigrant Women With Breast Cancer
  • Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin
  • (3D) Ultrasound Imaging Liver and Kidney
  • A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB Subtype DLBCL (ACE-LY-312)
  • A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis
  • A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies
  • Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread
  • Interactive Online Informational and Peer Support App for Patients With Low Anterior Resection Syndrome
  • Study of Niacin in Glioblastoma
  • A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
  • 2 Ablative RadioTherapy Treatments for Prostate Cancer
  • The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
  • Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT
  • Effect of Tumour Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)
  • Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
  • IBD Neoplasia Surveillance Pilot RCT
  • 68Ga-PSMA PET/CT in Prostate Cancer
  • Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program
  • Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma
  • Intermittent Androgen Deprivation Therapy With or Without Stereotactic Body Radiation Therapy for Molecularly Identified Hormone Sensitive Oligometastatic Prostate Cancer
  • Pancreatic Adenocarcinoma Signature Stratification for Treatment
  • Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
  • PSMA PET/CT Guided Intensification of Therapy in Patients at Risk of Advanced Prostate Cancer
  • Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
  • PROstate Cancer TReatment Optimization Via Analysis of Circulating Tumour DNA
  • Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer
  • A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
  • A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study
  • Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumours
  • A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
  • Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy.
  • Family History App in Personalized Medicine
  • MR Imaging Study Using the Northern Alberta Linac-MR (Northern LIGHTs - 1)
  • Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
  • LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers
  • Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumour Malignancies
  • Study of GEN-1 With NACT for Treatment of Ovarian Cancer (OVATION 2)
  • SWOG S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer
  • Phase 2 Trial of MRTX849 Plus Pembrolizumab for NSCLC With KRAS G12C Mutation KRYSTAL-7
  • Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment
  • An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas
  • A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
  • Glioma Supra Marginal Incision Trial
  • A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
  • A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumours
  • Symptom Screening Linked to Care Pathways
  • Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer
  • Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumours
  • Safety and Efficacy of [18F]PSMA-1007 Injection in Suspected Persistent or Recurrent Prostate Cancer.
  • Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumours And/Or Who Have No Satisfactory Treatment Options
  • NL-201 in Patients With Relapsed or Refractory Cancer
  • Does Routine Submucosal Injection Improve Complete Resection of 4-20 mm Neoplastic Colorectal Polyps?
  • Hypofractionated External-beam RadiOtherapy for Intact Cervical Cancer (HEROICC-Trial): A Feasibility Study
  • First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours
  • Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)
  • Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
  • Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)
  • A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma
  • Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
  • A Study of CC-99712, a BCMA Antibody-Drug Conjugate, in Participants With Relapsed and Refractory Multiple Myeloma
  • Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)
  • Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)
  • Pediatric Long-Term Follow-up and Rollover Study
  • A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML)
  • Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast Cancer
  • Dual Tracer (68Ga-DOTATATE and 18F-FDG) PET Imaging in G2 & G3 Gastroenteropancreatic Neuroendocrine Tumours
  • A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
  • 68Ga-HTK03149 for Use as a Diagnostic Radiopharmaceutical
  • Study of Cobolimab in Combination With Dostarlimab and Docetaxel in Advanced NSCLC Participants
  • Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
  • Surveillance AFter Extremity Tumour surgerY
  • Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)
  • The Pancreatic and Periampullary Resection Arginine Immunomodulation (PRIMe) Trial
  • Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Either Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease
  • Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumours
  • Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer
  • Study of JDQ443 in Patients With Advanced Solid Tumours Harboring the KRAS G12C Mutation
  • A Study of Pembrolizumab Added to the Standard First-Line Therapy of Cyclophosphamide, Bortezomib, and Dexamethasone (CyBorD) for NDMM NTE
  • Cannabis For Cancer-Related Symptoms
  • Pivotal, Randomized, Open-label Study of Optune® Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM
  • TAC T-cells for the Treatment of HER2-positive Solid Tumours
  • Study of Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations
  • A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung Cancer
  • A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy
  • Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
  • Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer
  • DRAGON 1- Training, Accreditation, Implementation and Safety Evaluation of Combined PVE/HVE
  • Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment
  • ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2)
  • Study of Lymphatic Drainage Mapping in Oropharyngeal Cancers
  • A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumours
  • A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)
  • AMG 404 in Patients With Advanced Solid Tumours.
  • Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumours
  • Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiation Therapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
  • Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
  • Safety and Effectiveness of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
  • The Cxbladder Hematuria Clinical Utility Study
  • A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer
  • A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia
  • A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
  • Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma
  • Vaginoscopy Compared to Traditional Hysteroscopy for Hysteroscopy Morcellation in Outpatient Clinic. A Randomized Trial
  • A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer
  • A Study of V937 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumours (V937-013)
  • An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumours
  • Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments
  • Concordance Between Liquid and Tissue Biopsy
  • A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumours Harboring ALK, ROS1, or NTRK1-3 Rearrangements
  • Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)
  • Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer
  • A Study of CC-97540, CD19-targeted NEX-T Chimeric Antigen Receptor (CAR) T Cells, in Subjects With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
  • A Study of Nivolumab and Ipilimumab in Combination With Transarterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer
  • A Study of Chemo Only Versus Chemo Plus Nivo With or Without BMS-986205, Followed by Post- Surgery Therapy With Nivo or Nivo and BMS-986205 in Patients With MIBC
  • A Study of BMS-986253 in Combination With Nivolumab or Nivolumab Plus Ipilimumab in Advanced Cancers
  • Stereotactic Body Radiation Therapy (SBRT) Post Prostatectomy
  • Adaptive RadioTherapy for OroPharynx Cancer
  • Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
  • Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery
  • Clinical Trial to Evaluate CT053 in Patients With Relapsed and/or Refractory Multiple Myeloma (LUMMICAR STUDY 2)
  • A Study to Determine Dose and Tolerability of CC-220 Monotherapy, in Combination With Dexamethasone, and in Combination With Dexamethasone and Daratumumab or Bortezomib in Subjects With Relapsed and Refractory Multiple Myeloma (MM)
  • HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer
  • Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)
  • SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
  • STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)
  • Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumours
  • Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate
  • Blinatumomab for MRD in Pre-B ALL Patients Following Stem Cell Transplant
  • A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder
  • Study of Sacituzumab Govitecan-hziy (IMMU-132) Versus Treatment of Physician's Choice in Participants With Metastatic or Locally Advanced Unresectable Urothelial Cancer
  • Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
  • A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma
  • A Study of SGN-STNV in Advanced Solid Tumours
  • Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumours Malignancies
  • Pembrolizumab Plus Lenvatinib for First-line Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma (1L nccRCC) (MK-3475-B61)
  • Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
  • Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
  • Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases
  • Efficacy and Safety of Olaparib, Olaparib + Bevacizumab Compared to Bevacizumab + 5-Fluorouracil (FU)
  • Postoperative Identification of Tumour Cells at the Lumpectomy Site of Patients With Early Breast Cancer
  • A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms
  • Potency pReservation In Prostate cAncer Patients Treated With UltraSound-guided Low-dose Rate Brachytherapy
  • Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
  • A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumours
  • Study of DS-1062A Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-LUNG01)
  • UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: A Phase 2 Trial
  • Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours (P3BEP)
  • Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis
  • Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)
  • Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)
  • Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)
  • A Study to Assess Safety and Efficacy of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-PD-1 Treatment
  • A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer
  • A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
  • Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
  • MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb
  • Evaluating the Dose Timing (Morning vs Evening) of Endocrine Therapy and Its Effects on Tolerability and Compliance
  • A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)
  • Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis
  • HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers
  • Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of Tomivosertib Combined With Paclitaxel in Advanced Breast Cancer
  • A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumours.
  • Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer
  • A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)